In Investigation One, you will examine slides of normal tissue. During this Investigation, you will:

1. View the following prepared slides under a microscope:

• normal skin tissue
• normal lung tissue
• normal breast tissue (active and inactive)

2. Observe the components of these normal tissues:

• Skin: dermis; epidermis; subcutaneous layer
• Lung: respiratory bronchioles; blood vessels, alveoli
• Breast: lobe; adipose cells

In Investigation Two, you will explore the factors that determine cell division and replication. During this Investigation, you will:

1. Construct a model of the cell cycle using tubing including the following phases:

• G1 Phase
• S Phase
• G2 Phase
• M Phase

2. Identify the following sub-phases of M Phase as:

• Prophase
• Metaphase
• Anaphase
• Telophase

3. Alter the cell cycle model to show how the cell stops and starts each phase.

In Investigation Three, you will explore the process of cell division in normal and in cancerous tissue. During this Investigation, you will:

1. Examine the role of contact inhibition in preventing cells from continuously dividing.

2. Model what happens when a normal cell is transformed into a cancerous cell.

3. View and compare prepared slides of normal and cancerous lung and breast tissue under a microscope.