ANALYZE IT

Complete the Analysis Questions in your SDR then discuss them as a class. 

• For each mutant protein model, was there a change in the amino acid sequence as compared to the wild type protein? 

• Compare the way the model wild-type protein looked to the way the model mutant proteins looked. For each mutant protein model, was there a change in the structure as compared to the wild-type protein? 

• Compare the rate of water transfer for the wild-type protein to the rate for each mutant. For each protein model, was there a change in the function of the protein as compared to the wild-type protein? 

• Describe any changes in function observed with the model mutant proteins. Use data to support your answer. 

• Look at the results in Table D. Did every change in amino acid sequence cause a change in protein structure? Explain your answer. 

• Look at the results in Table D. Did every change in protein structure cause a change in function? Explain your answer. 

• Are all mutations harmful? Explain your answer. 

GET FOCUSED

Complete the Focus Question in your SDR then discuss it as a class. 

• Can mutations in DNA cause changes in an organism? Explain.